Scientific Program

"Clinical Efficacy and Future Development of Pelareorep: A Novel Reovirus with Demonstrated Activity in Multiple Gastrointestinal Cancers"

"Which is more effective clinically, intravenous or intratumoral delivery? Data from circa 100 patients treated with oncolytic adenovirus TILT-123"

"Combination systemic oncolytic immunotherapy in patients with advanced neuroendocrine carcinoma"

"Cretostimogene (aka CG0070) for non-muscle invasive bladder cancer – a clinical update"

"Oncolytic virotherapy: A potential cornerstone for all IO modalities"

"CAN-2409: locally delivered viral immunotherapy for solid tumors"

"Phase I/II trial of measles virus infected adipose tissue derived mesenchymal stem cells in patients with recurrent ovarian cancer"

"A Phase 1 Clinical Trial to Evaluate Intravenous VSV-IFNß-NIS in Combination with Cemiplimab and Ipilimumab for Relapsed Peripheral T-Cell Lymphoma"

"Oncolytic HSV Synergizes with DNA-PKcs Inhibition to Treat Glioblastoma"

"Oncolytic Virus-Specific T Cell Receptor Activation Enhances CAR T Cell Potency, Persistence and Anti-Tumour Efficacy"

"Epigenetic Modulation of P300/CBP Boosts Delta-24-RGD-Induced Immune Cell Recruitment in Diffuse Midline Glioma"

"Immune responses elicited by rMV-SLAMblind oncolytic therapy exert a synergistic effect on the cancer therapy"

"Intranasal Nanoplatform and Potent Oncolytic Adenovirus Therapy for Glioblastoma"

"Disabling a key viral innate immunity antagonist converts measles vaccine into RIG-I–driven cancer immunotherapy"

"Oncolytic VSVdeltaM51 Activates NLRP1 Inflammasome Signaling While Wild-Type VSV Evades Innate Restriction"

"Beta-blocker mitigates perivascular macrophage mediated immunosuppression during oncolytic herpes virotherapy"

"The Abscopal Effect of Oncolytic HSV-1 Requires TLR9-Driven Plasmacytoid Dendritic Cell Activation"

"VET3-TGI: Interim Phase I Clinical data in Solid Tumours"

"Next generation Oncolytic immunotherapy for cancer treatment"

"Phase I Trial of Bone Marrow-Derived Mesenchymal Stem Cells Carrying Delta-24-RGD Delivered via Endovascular Selective Intra-arterial (ESIA) Infusion in Recurrent Glioma: Initial Report"

"CRISPR-Guided Evolution of Improved Delivery Systems for Genetically Encoded Immunotherapies"

"A Systemically Deliverable Vaccinia-Based Oncolytic Virus, VIR106, Demonstrates Potent Antitumor Activity After a Single Intravenous Dose"

"Oncolytic Virotherapy Expands and Reprograms T Cells into CAR-T Cells Within the Tumor Microenvironment"

"Oncolytic reovirus as an oral cancer immunotherapy"

"HLA-matched humanized mouse model to study pancreatic ductal adenocarcinoma"

"Persistent T cell Activation and Cytotoxicity against Human Glioblastoma Following Single Oncolytic Virus Treatment"

"Impact of Anti-viral vs Anti-tumour CD8 response on treatment with HSV"

"Intravesical Recombinant MVA Therapy Induces Local and Systemic Antitumor Immunity and Memory in an Orthotopic Murine Bladder Cancer Model"

"Intratumoural oncolytic HSV-1 reshapes the local and systemic immune landscape through CD8+ T cell reprogramming"

"A Next-Generation Systemic Platform for Tumor-Localized Expression of T-Cell Engagers and Immune Activator"

"Mesenchymal Stem Cells Delivering IL-33 Oncolytic Vaccinia Virus Enhance Antitumor Effects and Overcome PD-1 Inhibitor Resistance in Bladder Cancer"

"Innate, anti-viral and anti-tumor biomarkers associated with clinical responses to pelareorep"

"Integrative TCR-seq/Spatial transcriptomics studies correlate with survival in virotherapy-treated gliomas"

"Case series: Off-label treatment with T-VEC as an additive immunovirotherapy for aggressive NUT-carcinomas"

"Long Term Survival with Oncolytic Viral therapy: Final results of a Phase II study of Telomelysin (OBP-301) in combination with pembrolizumab in gastroesophageal (GEA) adenocarcinoma"

"Neutralizing antibodies as biomarkers and functional effectors in TILT-123 oncolytic adenovirus therapy"

"The combination of Delta-24-RGD and TIM-3 blockade enhances oncolytic virotherapy in diffuse midline glioma"

"Improved iRNA-LNP Therapeutic Performance Through 5’UTR-Restricted MicroRNA Detargeting"

"Comparative evaluation of oncolytic viruses reveals opposing preferences for glioblastoma subtypes"

"A Potent and Selective PHOX2B Promoter–Driven Oncolytic Adenovirus for Targeted Neuroblastoma Therapy"